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plasma aldosterone concentration  (Snibe Inc)

 
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    Snibe Inc plasma aldosterone concentration
    Plasma Aldosterone Concentration, supplied by Snibe Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasma+aldosterone+concentration/pmc13006190-127-14-0?v=Snibe+Inc
    Average 86 stars, based on 1 article reviews
    plasma aldosterone concentration - by Bioz Stars, 2026-07
    86/100 stars

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    Derivation of study cohort. The study comprised 2 cohorts: the discovery cohort, from the First Affiliated Hospital with Nanjing Medical University, and the validation cohort, derived from the Framingham Heart Study Third Generation cohort. In both cohorts, renin-independent aldosteronism was defined as plasma renin activity ≤ 1 µg/L/h and plasma aldosterone concentration ≥ 100 pg/mL. CVD, cardiovascular disease; n, number.

    Journal: Frontiers in Endocrinology

    Article Title: Data-driven cluster analysis and external validation identify phenotypic subgroups in renin-independent aldosteronism with differential cardiovascular risk and therapeutic implications

    doi: 10.3389/fendo.2025.1686480

    Figure Lengend Snippet: Derivation of study cohort. The study comprised 2 cohorts: the discovery cohort, from the First Affiliated Hospital with Nanjing Medical University, and the validation cohort, derived from the Framingham Heart Study Third Generation cohort. In both cohorts, renin-independent aldosteronism was defined as plasma renin activity ≤ 1 µg/L/h and plasma aldosterone concentration ≥ 100 pg/mL. CVD, cardiovascular disease; n, number.

    Article Snippet: Plasma aldosterone concentrations were measured using an enzyme-linked immunosorbent assay (ALPCO Diagnostics), and plasma renin activity was measured with a radioimmunoassay (DiaSorin).

    Techniques: Biomarker Discovery, Derivative Assay, Clinical Proteomics, Activity Assay, Concentration Assay

    Visualization of clustering results and patient distribution in the discovery cohort. (A) t-Distributed Stochastic Neighbor Embedding (t-SNE) plot visualizing high-dimensional data. (B) Patient distribution across clusters. (C) Standardized values (z-scores) of selected variables by cluster. All continuous variables were scaled (mean = 0, SD = 1). (D) The ribbons connect an individual cluster to a variable if the group mean is greater or less than the overall mean for the entire cohort. BMI, body mass index; BP, blood pressure; FBG, fasting blood glucose; FINS, fasting insulin; PAC, plasma aldosterone concentration; PRA, plasma renin activity; RIA, renin-independent aldosteronism; TC, total cholesterol; TG, triglycerides.

    Journal: Frontiers in Endocrinology

    Article Title: Data-driven cluster analysis and external validation identify phenotypic subgroups in renin-independent aldosteronism with differential cardiovascular risk and therapeutic implications

    doi: 10.3389/fendo.2025.1686480

    Figure Lengend Snippet: Visualization of clustering results and patient distribution in the discovery cohort. (A) t-Distributed Stochastic Neighbor Embedding (t-SNE) plot visualizing high-dimensional data. (B) Patient distribution across clusters. (C) Standardized values (z-scores) of selected variables by cluster. All continuous variables were scaled (mean = 0, SD = 1). (D) The ribbons connect an individual cluster to a variable if the group mean is greater or less than the overall mean for the entire cohort. BMI, body mass index; BP, blood pressure; FBG, fasting blood glucose; FINS, fasting insulin; PAC, plasma aldosterone concentration; PRA, plasma renin activity; RIA, renin-independent aldosteronism; TC, total cholesterol; TG, triglycerides.

    Article Snippet: Plasma aldosterone concentrations were measured using an enzyme-linked immunosorbent assay (ALPCO Diagnostics), and plasma renin activity was measured with a radioimmunoassay (DiaSorin).

    Techniques: Clinical Proteomics, Concentration Assay, Activity Assay

    Clinical characteristics of patients with RIA stratified by different clusters in the discovery cohort. The distribution of (A) age, (B) BMI, (C) systolic blood pressure, (D) diastolic blood pressure, (E) plasma aldosterone concentration, (F) plasma renin activity, (G) cortisol, (H) total cholesterol, (I) triglycerides, (J) fasting blood glucose, and (K) fasting insulin in different clusters in the discovery cohort. BMI, body mass index; BP, blood pressure; FBG, fasting blood glucose; FINS, fasting insulin; h, hour; PAC, plasma aldosterone concentration; PRA, plasma renin activity; RIA, renin-independent aldosteronism; TC, total cholesterol; TG, triglycerides. * P < 0.05; *** P < 0.001; **** P < 0.0001.

    Journal: Frontiers in Endocrinology

    Article Title: Data-driven cluster analysis and external validation identify phenotypic subgroups in renin-independent aldosteronism with differential cardiovascular risk and therapeutic implications

    doi: 10.3389/fendo.2025.1686480

    Figure Lengend Snippet: Clinical characteristics of patients with RIA stratified by different clusters in the discovery cohort. The distribution of (A) age, (B) BMI, (C) systolic blood pressure, (D) diastolic blood pressure, (E) plasma aldosterone concentration, (F) plasma renin activity, (G) cortisol, (H) total cholesterol, (I) triglycerides, (J) fasting blood glucose, and (K) fasting insulin in different clusters in the discovery cohort. BMI, body mass index; BP, blood pressure; FBG, fasting blood glucose; FINS, fasting insulin; h, hour; PAC, plasma aldosterone concentration; PRA, plasma renin activity; RIA, renin-independent aldosteronism; TC, total cholesterol; TG, triglycerides. * P < 0.05; *** P < 0.001; **** P < 0.0001.

    Article Snippet: Plasma aldosterone concentrations were measured using an enzyme-linked immunosorbent assay (ALPCO Diagnostics), and plasma renin activity was measured with a radioimmunoassay (DiaSorin).

    Techniques: Clinical Proteomics, Concentration Assay, Activity Assay